Showing 55 of 55

Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials.

Low Confidence Trial Design

2026 41090431

retatrutide

IUPHAR review: From foe to friend: Repurposing glucagon to treat obesity and type 2 diabetes.

Moderate Confidence Review

2026 41478576

retatrutide

Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.

High Confidence RCT

2025 40353578

tirzepatidesemaglutide

Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes.

High Confidence RCT

2025 40544432

cagrilintidesemaglutide

Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?

Low Confidence Case Report

2025 40210573

melanotan-ii

Strategic Design of Triple GLP-1R/GCGR/GIPR Agonists with Varied Receptor Potency: Achieving Comparable Glycemic and Weight Reduction Effects.

Low Confidence In Vitro

2025 40958513

retatrutide

Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors.

Moderate Confidence Review

2025 40607385

semaglutideretatrutidebpc-157

The Clinical Application of GLP-1RAs and GLP-1/GIP Dual Receptor Agonists Based on Pharmacological Mechanisms: A Review.

Moderate Confidence Review

2025 41312047

tirzepatide

Targeting the incretin system in obesity and type 2 diabetes mellitus.

Moderate Confidence Review

2024 38632474

semaglutidetirzepatideretatrutideliraglutide

Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.

Moderate Confidence RCT

2023 37366315

retatrutide

Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.

High Confidence RCT

2023 37952131

semaglutide

Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application.

Low Confidence Review

2023 37110771

thymosin-alpha-1

Thymosin β4 and Actin: Binding Modes, Biological Functions and Clinical Applications.

Low Confidence Review

2023 36464872

thymosin-beta-4

Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet.

Moderate Confidence RCT

2023 36909866

matrixyl

Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial.

Moderate Confidence RCT

2023 37268435

ss-31

Into the Light: Afamelanotide and the Treatment of Erythropoietic Protoporphyria in the United States.

Moderate Confidence Observational

2023 37683058

melanotan-i

Tirzepatide Once Weekly for the Treatment of Obesity.

High Confidence RCT

2022 35658024

tirzepatide

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

Low Confidence Review

2021 34267654

bpc-157

Once-Weekly Semaglutide in Adults with Overweight or Obesity.

High Confidence RCT

2021 33567185

semaglutide

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.

High Confidence RCT

2021 34170647

tirzepatidesemaglutide

A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema.

Low Confidence Observational

2020 32674280

ara-290

Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study.

Low Confidence Observational

2020 31134751

snap-8

Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.

Low Confidence In Vitro

2020 33237528

thymalin

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.

High Confidence RCT

2019 31599840

bremelanotide

Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity.

Low Confidence Animal Study

2017 28955242

pe-22-28

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

High Confidence RCT

2016 27633186

semaglutide

Missing data in clinical trials for weight management.

Moderate Confidence Review

2016 26418188

semaglutidetirzepatideretatrutideliraglutide

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.

High Confidence RCT

2015 26132939

liraglutide

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.

Low Confidence Animal Study

2015 25738459

mots-c

Afamelanotide for Erythropoietic Protoporphyria.

High Confidence RCT

2015 26132941

melanotan-i

Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients.

Moderate Confidence RCT

2014 25331030

ipamorelin

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

Low Confidence Observational

2014 25176261

selank

Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.

Low Confidence Observational

2013 23099431

ghrp-6

The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study.

Moderate Confidence RCT

2013 23417317

argireline

Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats.

Low Confidence Animal Study

2012 22732845

tb-500thymosin-beta-4

Tesamorelin: a review of its use in the management of HIV-associated lipodystrophy.

Low Confidence Review

2011 21668043

tesamorelin

Cathelicidin LL-37: a multitask antimicrobial peptide.

Low Confidence Review

2010 20049649

ll-37

Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors.

Moderate Confidence Review

2009 19801361

semaglutide

Hexarelin: a multi-receptor peptide.

Low Confidence Review

2008 18787392

hexarelin

PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.

Low Confidence Animal Study

2008 18061177

kpv

The effect of tripeptide-copper complex on human hair growth in vitro.

Low Confidence In Vitro

2007 17703734

ghk-cu

Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin.

Low Confidence RCT

2006 16847171

ghk-cu

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.

Moderate Confidence RCT

2006 16352683

cjc-1295

Delta sleep-inducing peptide (DSIP): a still unresolved riddle.

Low Confidence Review

2006 16539679

dsip

International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function.

Moderate Confidence Review

2005 16382107

ipamorelinghrp-6hexarelin

Better reporting of harms in randomized trials: an extension of the CONSORT statement.

High Confidence Review

2004 15545678

semaglutidetirzepatideretatrutide

AOD-9604 Metabolic.

Low Confidence Review

2004 15134286

aod-9604

Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth.

Low Confidence Animal Study

2003 14554208

bpc-157

Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.

Low Confidence In Vitro

2003 12937682

epitalon

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.

Low Confidence In Vitro

2001 11371646

humanin

A novel pentadecapeptide, BPC 157, blocks the stereotypy produced acutely by amphetamine and the development of haloperidol-induced supersensitivity to amphetamine.

Low Confidence Animal Study

1998 9547930

bpc-157

[Effectiveness of semax in acute period of hemispheric ischemic stroke (a clinical and electrophysiological study)].

Low Confidence Observational

1997 11517472

semax

The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides.

Low Confidence Animal Study

1994 7904712

bpc-157

Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration.

Low Confidence Observational

1993 8329825

sermorelin

Hyperglycemic action of synthetic C-terminal fragments of human growth hormone.

Low Confidence Animal Study

1978 645904

frag-176-191