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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.

in-vitro • 2001 • ID: 11371646

Low Confidence In Vitro

Primary source: [Open]

Linked compounds: humanin

Outcomes summary

Foundational report describing the peptide humanin as a 'rescue factor' in experimental models of neuronal cell death associated with familial Alzheimer's disease genes and amyloid-beta–related insults.

Limitations

Primarily experimental model systems; does not establish human clinical efficacy; subsequent work explores analogs and mechanisms.

Notes

Primary source: PMID 11371646.