Literature
Curated studies, trials, and reviews. Each entry is labeled by study type and confidence tier.
IUPHAR review: From foe to friend: Repurposing glucagon to treat obesity and type 2 diabetes.
retatrutide
Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials.
retatrutide
Strategic Design of Triple GLP-1R/GCGR/GIPR Agonists with Varied Receptor Potency: Achieving Comparable Glycemic and Weight Reduction Effects.
retatrutide
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity.
tirzepatidesemaglutide
Immunogenicity of therapeutic peptide products: bridging the gaps regarding the role of product-related risk factors.
semaglutideretatrutidebpc-157
The Clinical Application of GLP-1RAs and GLP-1/GIP Dual Receptor Agonists Based on Pharmacological Mechanisms: A Review.
tirzepatide
Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes.
cagrilintidesemaglutide
Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?
melanotan-ii
Lilly's triple agonist, retatrutide, delivered weight loss of up to an average of 71.2 lbs along with substantial relief from osteoarthritis pain in first successful Phase 3 trial (TRIUMPH-4)
retatrutide
Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties
epitalon
Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study
bpc-157
Body Protective Compound-157 in Orthopedic Applications: A Systematic Review
bpc-157
Cagrilintide-Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes
cagrilintidesemaglutide
Don't Risk Using Tanning Products Containing Melanotan
melanotan-imelanotan-ii
Targeting the incretin system in obesity and type 2 diabetes mellitus.
semaglutidetirzepatideretatrutideliraglutide
Effect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study
bpc-157
CagriSema Demonstrates Superior Weight Loss in Adults with Obesity or Overweight in the REDEFINE 1 Trial
cagrilintidesemaglutide
Tirzepatide for Obstructive Sleep Apnea: The SURMOUNT-OSA Trial
tirzepatide
Melanotan I: LiverTox Database Entry
melanotan-i
Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial.
retatrutide
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
semaglutide
Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application.
thymosin-alpha-1
Thymosin β4 and Actin: Binding Modes, Biological Functions and Clinical Applications.
thymosin-beta-4
Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet.
matrixyl
Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial.
ss-31
Into the Light: Afamelanotide and the Treatment of Erythropoietic Protoporphyria in the United States.
melanotan-i
Reminder of Serious Health Risks with Melanotan 2 Self-Tan Products
melanotan-ii
Tirzepatide Once Weekly for the Treatment of Obesity.
tirzepatide
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.
bpc-157
Once-Weekly Semaglutide in Adults with Overweight or Obesity.
semaglutide
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.
tirzepatidesemaglutide
A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema.
ara-290
Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study.
snap-8
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
thymalin
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.
bremelanotide
Saniona's Tesofensine Meets Primary and Secondary Endpoints in Phase 3 Obesity Registration Trial (Viking Study)
tesofensine
Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity.
pe-22-28
Missing data in clinical trials for weight management.
semaglutidetirzepatideretatrutideliraglutide
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
semaglutide
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.
liraglutide
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.
mots-c
Afamelanotide for Erythropoietic Protoporphyria.
melanotan-i
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients.
ipamorelin
[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].
selank
Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.
ghrp-6
The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study.
argireline
Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats.
tb-500thymosin-beta-4
Tesamorelin: a review of its use in the management of HIV-associated lipodystrophy.
tesamorelin
Cathelicidin LL-37: a multitask antimicrobial peptide.
ll-37
Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors.
semaglutide
Hexarelin: a multi-receptor peptide.
hexarelin
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.
kpv
Effect of Tesofensine on Bodyweight Loss, Body Composition, and Quality of Life in Obese Patients: A Randomised, Double-Blind, Placebo-Controlled Trial
tesofensine
The effect of tripeptide-copper complex on human hair growth in vitro.
ghk-cu
Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin.
ghk-cu
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
cjc-1295
Delta sleep-inducing peptide (DSIP): a still unresolved riddle.
dsip
Oral Treatment with MK-677, a Novel Growth Hormone Secretagogue, in Obese Patients: A Double-Blind, Placebo-Controlled Study
ibutamoren
International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function.
ipamorelinghrp-6hexarelin
Better reporting of harms in randomized trials: an extension of the CONSORT statement.
semaglutidetirzepatideretatrutide
AOD-9604 Metabolic.
aod-9604
Nutritional and Hormonal Responses to an Oral Secretagogue in Obese Patients
ibutamoren
Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth.
bpc-157
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.
epitalon
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.
humanin
A novel pentadecapeptide, BPC 157, blocks the stereotypy produced acutely by amphetamine and the development of haloperidol-induced supersensitivity to amphetamine.
bpc-157
[Effectiveness of semax in acute period of hemispheric ischemic stroke (a clinical and electrophysiological study)].
semax
The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides.
bpc-157
Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration.
sermorelin
Hyperglycemic action of synthetic C-terminal fragments of human growth hormone.
frag-176-191