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Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors.

review • 2009 • ID: 19801361

Moderate Confidence Review

Primary source: [Open]

Linked compounds: semaglutide

Outcomes summary

Mechanism/pharmacology review comparing GLP-1 receptor agonists and DPP-4 inhibitors, covering differences in chemistry, receptor signaling, and clinical pharmacology at a class level.

Limitations

Older review that predates some newer agents; may not reflect later-generation molecules and newer clinical evidence.

Notes

Primary source: PMID 19801361 (see PubMed link on this page).