Afamelanotide for Erythropoietic Protoporphyria.
High Confidence RCTPrimary source: [Open]
Linked compounds: melanotan-i
Outcomes summary
Randomized trial evaluating afamelanotide (a melanocortin peptide; often discussed under Melanotan I/afamelanotide) for erythropoietic protoporphyria, reporting improved tolerance of light exposure and reduced phototoxicity-related outcomes versus placebo in the studied setting.
Limitations
Rare-disease population; outcomes are condition-specific; device/implant formulation limits generalizability to other contexts.
Notes
Primary source: PMID 26132941.