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Thymosin Beta-4

Also known as: TB4, Tβ4

Thymosin Peptide Actin (binding)Tissue Repair Pathways (context-dependent)
Last updated: 1/22/2026 Last reviewed: 1/22/2026

At a Glance

Thymosin β4 (Tβ4) is a peptide studied for actin-binding and potential roles in tissue repair and regeneration in preclinical settings.

⚠️ Research context: This page summarizes research only and does not provide medical advice or dosing recommendations.


Mechanism of Action (High Level)

Thymosin β4 is well-known for actin binding, with downstream effects described across multiple cell types and model systems.


Evidence Summary

Low Confidence Review ≤3 Years

A review discusses binding modes, biological functions, and clinical applications (with evidence varying by indication). [PMID: 36464872]


Safety & Unknowns (High Level)

  • Human efficacy/safety depends on indication and formulation; much of the literature is preclinical.

Key Studies

YearTypeTopicCitation
2023ReviewFunctions and clinical applications overview [PMID: 36464872]

📚 See linked items in the Literature section.