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Thymosin Alpha-1

Also known as: Thymalfasin, Zadaxin

Thymosin Peptide Immune Signaling Pathways (context-dependent)
Last updated: 1/22/2026 Last reviewed: 1/22/2026

At a Glance

Thymosin alpha-1 (often referred to as thymalfasin) is studied as an immunomodulatory peptide in a variety of clinical and preclinical contexts.

⚠️ Evidence varies: This page summarizes research only and does not provide medical advice or dosing recommendations.


Mechanism of Action (High Level)

Reported effects involve immune signaling and innate/adaptive responses, but mechanisms and clinical relevance depend heavily on indication and study design.


Evidence Summary

Low Confidence Review ≤3 Years

Review literature discusses thymosin alpha-1’s proposed mechanisms and applications in viral infectious diseases. [PMID: 37110771]


Safety & Unknowns (High Level)

  • Safety depends on indication, co-therapies, and study context; consult primary sources and systematic reviews.

Key Studies

YearTypeTopicCitation
2023ReviewMechanisms and clinical application in viral infectious diseases [PMID: 37110771]

📚 See linked items in the Literature section.