Snap-8
Also known as: Acetyl Octapeptide-3
At a Glance
Snap-8 (acetyl octapeptide-3) is a cosmetic peptide used in topical skincare products. Evidence and tolerability are formulation-specific, and many studies evaluate multi-ingredient products rather than isolated acetyl octapeptide-3.
⚠️ Educational Only: This page summarizes cosmetic research and intentionally does not include protocols/dosing.
Mechanism of Action (TBD)
Often described as “Argireline-like” in cosmetic framing; mechanistic claims should be validated against primary sources for a given formulation.
Evidence Summary
Microneedle patch study (multi-ingredient)
Low Confidence Observational ≤3 YearsA monocentric clinical study of hyaluronic-acid microneedle patches containing multiple bioactives (including acetyl octapeptide-3) reported improvements in measured skin properties and good tolerability; attribution to a single ingredient is not possible. [PMID: 31134751]
Safety & Unknowns
- Topical tolerability varies by formulation and individual sensitivity.
- Multi-ingredient formulations limit causal attribution to acetyl octapeptide-3 alone.
Regulatory Status
| Region | Status |
|---|---|
| United States (FDA) | Cosmetic ingredient (not an approved drug) |
| European Union (EMA) | Cosmetic ingredient (not an approved drug) |
| WADA | Not typically addressed as a drug class; check current list if relevant |
Changelog
| Date | Change |
|---|---|
| 2026-01-23 | Added dossier and linked primary literature |